Publication References

Adenovirus/Lentivirus/Retrovirus/AAV and RNAi  Services performed by Welgen Inc. have been directly referenced by the following publications:

Jose A. Martina and Rosa Puertollano. 2013. Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes. J Cell Biol. 2013 200(4): 475–491.

Karen G. Shadrach, Mary E. Rayborn, Joe G. Hollyfield, and Vera L. Bonilha. 2013. DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE.) PLoS One. 2013; 8(7): e67983.

Birkhäuser FD, Koya RC, Neufeld C, Rampersaud EN, Lu X, Micewicz ED, Chodon T, Atefi M, Kroeger N,Chandramouli GV, Li G, Said JW, McBride WH, Kabbinavar FF, Ribas A, Pantuck AJ, Belldegrun AS,Riss J. 2013. Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models. J Immunother. 2013. 36(2):102-11.

Gao A, Kantarci A, Herrera B, Gao H, Van Dyke TE. 2013. A critical role for suppressors of cytokinesignaling 3 in regulating LPS-induced transcriptional activation of matrix metalloproteinase-13 in osteoblasts. PeerJ. 2013 Mar 5;1:e51

Proszynski TJ, Sanes JR. 2013. Amotl2 interacts with LL5β, localizes to podosomes and regulates postsynaptic differentiation in muscle. J Cell Sci. 2013 126(Pt 10):2225-35

Rodrigues PH, Reyes L, Chadda AS, Bélanger M, Wallet SM, Akin D, Dunn W Jr, Progulske-Fox A. 2012 Porphyromonas gingivalis Strain Specific Interactions with Human Coronary Artery Endothelial Cells: A Comparative Study. PLoS One. 2012;7(12):e52606.

Wang GX, Zhan YA, Hu HL, Wang Y, Fu B. 2012 Mesenchymal stem cells modified to express interferon-β inhibit the growth of prostate cancer in a mouse model. J Int Med Res. 2012. 40(1):317-27.

Sizemore ST, Keri RA. 2012. The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression.  Biol Chem. 2012 Jul 13;287(29):24631-40.

Killen MW, Stults DM, Wilson WA, Pierce AJ 2012 Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes. BMC Mol Biol. 2012 13(1):33

Blache CA, Manuel ER, Kaltcheva TI, Wong AN, Ellenhorn JD, Blazar BR, Diamond DJ. 2012. Systemic Delivery of Salmonella typhimurium Transformed with IDO shRNA Enhances Intratumoral Vector Colonization and Suppresses Tumor Growth. Cancer Res. 2012 .72(24):6447-56.

Emeline F. Nandrot, Kathryn E. Silva, Christina Scelfo, Silvia C. Finnemann. 2012. Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin. Biol Cell. 2012. 104(6): 326–341.

Enrico A. Duru, Yuyang Fu, and Mark G. Davies. 2012. Src regulates sphingosine-1-phosphate mediated smooth muscle cell migration. J Surg Res. 2012. 175(1): 30–34.

Conforto TL, Zhang Y, Sherman J, Waxman DJ. 2012. Impact of CUX2 on the Female Mouse Liver Transcriptome: Activation of Female-Biased Genes and Repression of Male-Biased Genes. Mol Cell Biol. 2012 Nov;32(22):4611-27.

Martina JA, Chen Y, Gucek M, Puertollano R. 2012. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy. 2012 Jun;8(6):903-14.

Sureshbabu A, Okajima H, Yamanaka D, Tonner E, Shastri S, Maycock J, Szymanowska M, Shand J, Takahashi S, Beattie J, Allan G, Flint D. 2012. IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF-7 human breast cancer cells. J Cell Sci. 2012 Apr 1;125(Pt 7):1693-705.

Wojciak-Stothard B, Zhao L, Oliver E, Dubois O, Wu Y, Kardassis D, Vasilaki E, Huang M, Mitchell JA, Harrington LS, Prendergast GC, Wilkins MR. 2012. Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia. Circ Res. 2012 May 25;110(11):1423-34

Zhao X, Feng D, Wang Q, Abdulla A, Xie XJ, Zhou J, Sun Y, Yang ES, Liu LP, Vaitheesvaran B, Bridges L, Kurland IJ, Strich R, Ni JQ, Wang C, Ericsson J, Pessin JE, Ji JY, Yang F. 2012. Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest. 2012 Jul 2;122(7):2417-27.

Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, Russell AP, Gerber AN, Bai X, Yan Z, NosekTM, Brotto M, Hoppel CL, Jain MK. 2012. Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation.  Proc Natl Acad Sci U S A. 109(17):6739-44.

Hu SI, Katz M, Chin S, Qi X, Cruz J, Ibebunjo C, Zhao S, Chen A, Glass DJ. 2012. MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscleSci Signal. 5(211): ra14

Doiron B, Hu W, Norton L, Defronzo RA. 2012. Lentivirus shRNA Grb10 targeting the pancreas inducesapoptosis and improved glucose tolerance due to decreased plasma glucagon levels. 2012 Diabetologia.55(3):719-28.

Lakadamyali M, Babcock H, Bates M, Zhuang X, Lichtman J. 2012. 3D multicolor super-resolution imaging offers improved accuracy in neuron tracing.  2012. PLoS One. 7(1):e30826.

Minetti GC, Feige JN, Rosenstiel A, Bombard F, Meier V, Werner A, Bassilana F, Sailer AW, Kahle P, Lambert C, Glass DJ, Fornaro M. 2011. Gαi2 signaling promotes skeletal muscle hypertrophy, myoblast differentiation, and muscle regeneration. 2011 Sci Signal. 4(201):ra80.

Fan L, Benson HL, Vittal R, Mickler EA, Presson R, Fisher AJ, Cummings OW, Heidler KM, Keller MR, Burlingham WJ, Wilkes DS. 2011. Neutralizing IL-17 prevents obliterative bronchiolitis in murineorthotopic lung transplantation. 2011. Am J Transplant. 11(5):911-22.

Shi J, Luo L, Eash J, Ibebunjo C, Glass DJ. 2011. The SCF-Fbxo40 complex induces IRS1 ubiquitinationin skeletal muscle, limiting IGF1 signaling. 2011 Dev Cell. 21(5):835-47

Qiang L, Lin HV, Kim-Muller JY, Welch CL, Gu W, Accili D. 2011. Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation. 2011 Cell Metab.14(6):758-67

Vergarajauregui S, Martina J A and Puertollano R. 2011. LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV. 2011 J Cell Sci. 124:459-68

Cooper PR, Kurten RC, Zhang J, Nicholls DJ, Dainty IA, Panettieri RA. 2011. Formoterol and salmeterolinduce a similar degree of β2-adrenoceptor tolerance in human small airways but via differentmechanisms. 2011 Br J Pharmacol. 163(3):521-32.

Pickens SR, Chamberlain ND, Volin MV, Mandelin AM 2nd, Agrawal H, Matsui M, Yoshimoto T, ShahraraS. 2011. Local expression of interleukin-27 ameliorates collagen-induced arthritis. 2011. Arthritis Rheum.63(8):2289-98.

Brown JD, Oligino E, Rader DJ, Saghatelian A, Plutzky J. 2011. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011. PLoS One. 6(7):e21209.

Ishikawa M, Iwamoto T, Nakamura T, Doyle A, Fukumoto S, Yamada Y. 2011.

Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation. 2011. J Cell Biol. 193(7):1257-74

Wei H, Zou H, Sheikh AM, Malik M, Dobkin C, Brown WT, Li X. 2011. IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation. 2011. J Neuroinflammation.  19;8:52.

Parikh K, Duysen EG, Snow B, Jensen NS, Manne V, Lockridge O, Chilukuri N. 2011.

Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds. 2011. J Pharmacol Exp Ther. 337(1):92-101.

Lelouvier B, Puertollano R. 2011. Mucolipin-3 regulates luminal calcium, acidification, and membrane fusion in the endosomal pathway. 2011. J Biol Chem. 286(11):9826-32.

Duysen EG, Parikh K, Aleti V, Manne V, Lockridge O, Chilukuri N. 2011. Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon. 2011. Gene Ther. 18(3):250-7.

Arun P, Aleti V, Parikh K, Manne V, Chilukuri N 2011. Senescence marker protein 30 (SMP30) expressionin eukaryotic cells: existence of multiple species and membrane localization. 2011. PLoS One. 6(2):e16545

Yan C, Cao J, Wu M, Zhang W, Jiang T, Yoshimura A, Gao H. 2010. Suppressor of cytokine signaling 3 inhibits LPS-induced IL-6 expression in osteoblasts by suppressing CCAAT/enhancer-binding protein {beta} activity. J Biol Chem. 2010 Nov 26;285(48):37227-39.

Nargis Nasrin, Xiaoping Wu, Eric Fortier, Yajun Feng, Olivia Claire Bare’, Sumiao Chen, Xianglin Ren, Zhidan Wu, Ryan S. Streeper and Laura Bordone. 2010. SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells. 2010. J Biol Chem.  285, 31995-32002.

 Xudong Liao, Saptarsi M. Haldar, Yuan Lu, Darwin Jeyaraj, Kaavya Paruchuri, Monika Nahori, YingjieCui, Klaus H. Kaestner and Mukesh K. Jain, 2010. Krüppel-like factor 4 regulates pressure-induced cardiac hypertrophy. 2010 Journal of Molecular and Cellular Cardiology 49: 334-338

Jones A, Hwang DJ, Narayanan R, Miller DD, Dalton JT. 2010 Effects of a Novel Selective Androgen Receptor Modulator on Dexamethasone-Induced and Hypogonadism-Induced Muscle Atrophy. 2010 Endocrinology. 151(8):3706-19.

Chau MD, Gao J, Yang Q, Wu Z, Gromada J. 2010 Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway. 2010. Proc Natl Acad Sci U S A. 107(28):12553-8.

Padmamalini Kannan-Thulasiraman, Darcie D. Seachrist, Ganapati H. Mahabeleshwar, Mukesh K. Jain, and Noa Noy 2010. Fatty acid-binding protein 5 and PPARbeta/delta are critical mediators of epidermal growth factor receptor-induced carcinoma cell growth. 2010 J Biol Chem. April 27, 2010

Jennifer L. Yori, Emhonta Johnson, Guangjin Zhou, Mukesh K. Jain, and Ruth A. Keri. 2010. Krüppel-like factor 4 (KLF4) inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression. 2010 J Biol Chem. March 31, 2010

Rangwala SM, Wang X, Calvo JA, Lindsley L, Zhang Y, Deyneko G, Beaulieu V, Gao J, Turner G, Markovits J. 2010. Estrogen-related receptor {gamma} is a key regulator of muscle mitochondrial activity and oxidative capacity. 2010 J Biol Chem. 285(29):22619-29

Tomasz J. Proszynski, Jacinthe Gingras, Gregorio Valdez, Konrad Krzewski and Joshua R. Sanes. 2009.Podosomes are present in a postsynaptic apparatus and participate in its maturation. 2009 Proc NatlAcad Sci U S A  106 (43): 18373-18378.

Jose A. Martina  , Benjamin Lelouvier  and Rosa Puertollano. 2009. The Calcium Channel Mucolipin-3 is a Novel Regulator of Trafficking Along the Endosomal Pathway 2009 Traffic 10: 1143-1156.

Sandra Kleiner, Van Nguyen-Tran, Olivia Baré, Xueming Huang, Bruce Spiegelman,§ and Zhidan Wu 2009. PPARδ Agonism Activates Fatty Acid Oxidation via PGC-1α but Does Not Increase Mitochondrial Gene Expression and Function. 2009 J Biol Chem.  284(28): 18624–18633.

Shah AG., Meyer J. Friedman, Shanshan Huang, Meredith Roberts, Xiao-Jiang Li and Shihua Li. 2009.Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.2009 Hum. Mol. Genet 18(21):4141-4152.

Li J.; Tomonaga Ichikawa ; Luis Villacorta ; Joseph S. Janicki ; Gregory L. Brower ; Masayuki Yamamoto ; and Taixing Cui. 2009. Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress.2009 Arterioscler Thromb Vasc Biol. 29(11):1843-50.

Tomonaga Ichikawa, Jinqing Li, Xiaoyu Dong, Jay D. Potts, Dong-Qi Tang, Dong-Sheng Li, and TaixingCui, 2009. Ubiquitin carboxyl terminal hydrolase L1 negatively regulates TNFα-mediated vascular smooth muscle cell proliferation via suppressing ERK activation. 2009. Biochemical and Biophysical Research Communications 391:852-856

Ames R S; Lu Quinn. 2009 Viral-mediated gene delivery for cell-based assays in drug discovery. 2009 Expert Opinion on Drug Discovery. 4 (3): 243-256

Roztocil E, Nicholl S, Davies M. 2009 Mechanisms of sphingosine-1-phosphate-induced akt-dependent smooth muscle cell migration. 2009 Surgery. 145(1):34-41.

Zoltan Arany, Shi-Yin Foo, Yanhong Ma, Jorge L. Ruas1, Archana Bommi-Reddy, Geoffrey Girnun1, Marcus Cooper, Dina Laznik, Jessica Chinsomboon, Shamina M. Rangwala, Kwan Hyuck Baek, Anthony Rosenzweig & Bruce M. Spiegelman. 2008, HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1. 2008  Nature 451, 1008-1012.

Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM. 2008 Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation.2008 Proc Natl Acad Sci U S A. 105(12):4721-4726.

Roztocil E, Nicholl S, Davies M. 2008 Sphingosine-1-phosphate–induced oxygen free radical generation in smooth muscle cell migration requires Gα12/13 protein-mediated phospholipase C activation . 2008 J Vascular Surg.  46(6):1253 – 1259. 

Jin P, Zhang J, Sumariwalla PF, Ni I, Jorgensen B, Crawford D, Phillips S, Feldmann M, Shepard HM, Paleolog EM. 2008. Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis. 2008 Arthritis Res Ther. Jul 1;10(4):R73.

Wang B, Haldar SM, Lu Y, Ibrahim OA, Fisch S, Gray S, Leask A, Jain MK. 2008. The Kruppel-like factor KLF15 inhibits connective tissue growth factor (CTGF) expression in cardiac fibroblasts. 2008 J Mol Cell Cardiol. 2008 May 20.

Guoqing Sheng, Xingshun Xu, Yung-Feng Lin, Chuan-En Wang, Juan Rong, Dongmei Cheng, JunminPeng, Xiaoyan Jiang, Shi-Hua Li and Xiao-Jiang Li, 2008.

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. J. Clin. Invest. 10.1172

Kai Chen, Michael T. Kirber, Hui Xiao, Yu Yang, and John F. Keaney, Jr. 2008  Regulation of ROS signal transduction by NADPH oxidase 4 localization. J. Cell Biology, 181:1129-1139

Clarke B, Drujan D, Willis M, Murphy L, Corpina R, Burova E, Rakhilin S, Stitt T, Patterson C, Latres E. 2007 The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle . 2007 Cell Metab. 6 (5): 376 – 385.

Gray S, Wang B, Orihuela Y, Hong EG, Fisch S, Haldar S, Cline GW, Kim JK, Peroni OD, Kahn BB, Jain MK. 2007. Regulation of gluconeogenesis by Krüppel-like factor 15. 2007 Cell Metab. 5(4):305-12.

Thirugnana Subramanian and Govindaswamy Chinnadurai. 2007 Temperature Sensitive Replication-Competent Adenovirus shRNA Vectors to Study Cellular Genes in Virus-Induced Apoptosis. 2007 In: Methods in Molecular Medicine, Volume 130, p125-134.

Haiyan Xu, Denise Wilcox, Phong Nguyen, Martin Voorbach, Harriet Smith, Stevan Brodjian, Thomas Suhar, Regina Reilly,  Peer Jacobson, Christine A. Collins, Katherine Landschulz, Terry Surowy. 2007. Hepatic knockdown of stearoyl-COA desaturase 1 via RNA interference in obese mice decreases lipid content and changes fatty acid composition. 2007 In: Frontiers in Bioscience 12, 3781-3794

Sheng G, Chang GQ, Lin JY, Yu ZX, Fang ZH, Rong J, Lipton SA, Li SH, Tong G, Leibowitz SF, Li XJ. 2006. Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior. 2006 Nature Medcine. 12:526-33.

Zheng X, Koropatnick J, Li M, Zhang X, Ling F, Ren X, Hao X, Sun H, Vladau C, Franek JA, Feng B, Urquhart BL, Zhong R, Freeman DJ, Garcia B, Min WP. 2006. Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference. 2006 J Immunol.177(8):5639-46.

Hideaki Miyoshi, Sandra C. Souza, Hui-Hong Zhang , Katherine J. Strissel , Marcelo A. Christoffolete, Julia Kovsan, Assaf Rudich, Fredric B. Kraemer, Antonio C. Bianco, Martin S. Obin, and Andrew S. Greenberg. 2006. Perilipin Promotes Hormone-sensitive Lipase-mediated Adipocyte Lipolysis via Phosphorylation-dependent and -independent Mechanisms. 2006 J. Biol. Chem. 281:15837-15844.

Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC. 2006. Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1{alpha} transcription and mitochondrial biogenesis in muscle cells. 2006 Proc Natl Acad Sci U S A.103(39):14379-84.

Liu Z, Ahn JY, Liu X, Ye K. 2006. Ebp1 isoforms distinctively regulate cell survival and differentiation. 2006 Proc Natl Acad Sci U S A. 103(29):10917-22..

Hiranmoy Das, Ajay Kumar, Zhiyong Lin, Willmar D. Patino , Paul M. Hwang , Mark W. Feinberg, PradipK. Majumder , and Mukesh K. Jain,  2006. Kruppel-like factor 2 (KLF2) regulates proinflammatoryactivation of monocytes. 2006 Proc Natl Acad Sci U S A. 103(17):6653-6658.

McGuire JR, Rong J, Li SH, Li XJ.. 2006 Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. 2006 J Biol Chem.281:3552-9

Hideaki Miyoshi, Sandra C. Souza, Hui-Hong Zhang, Katherine J. Strissel, Marcelo A. Christoffolete, Julia Kovsan, Assaf Rudich, Fredric B. Kraeme, Antonio C. Bianco, Martin S. Obin, and Andrew S. Greenberg. 2006. Perilipin Promotes Hormone-sensitive Lipase-mediated Adipocyte Lipolysis via Phosphorylation-dependent and -independent Mechanisms. 2006 J. Biol. Chem., 281:15837-15844.

Ahn JY, Liu X, Liu Z, Pereira L, Cheng D, Peng J, Wade PA, Hamburger AW, Ye K. 2006. Nuclear Aktassociates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. 2006 EMBO J. 25(10):2083-95.

Juan Rong, John R. McGuire, Zhi-Hui Fang, Guoqing Sheng, Ji-Yeon Shin, Shi-Hua Li, and Xiao-Jiang Li. 2006. Regulation of Intracellular Trafficking of Huntingtin-Associated Protein-1 Is Critical for TrkA Protein Levels and Neurite Outgrowth . 2006 J Neurosci.26(22): 6019-6030;

Xu H, Wilcox D, Nguyen P, Voorbach M, Suhar T, Morgan SJ, An WF, Ge L, Green J, Wu Z, Gimeno RE, Reilly R, Jacobson PB, Collins CA, Landschulz K, Surowy T. 2006. Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile. Biochem Biophys Res Commun. 349(1):439-48.

Seungil Ro, Sung Jin Hwang, Tamas Ordog, and Kenton M. Sanders. 2005. Adenovirus-based short hairpin RNA vectors containing an EGFP marker and mouse U6, human H1, or human U6 promoter.2005 BioTechniques  38: 625-627.

Rong R, Tang X, Gutmann DH, Ye K. 2004  Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L. 2004 Proc Natl Acad Sci U S A.101(52):18200-5.